Test Code IFLC Immunoglobulin Free Chains
Clinical Information
Elevated kappa and lambda (K/L) free light chain (FLC) may occur due to polyclonal hypergammaglobulinemia or impaired renal clearance. A specific increase in FLC (e.g., FLC K:L ratio) must be demonstrated for diagnostic purposes. This assay has not been established for use with the pediatric population. Moderate-to-marked lipemia may interfere with the ability to perform testing.
Synonym
- IFLC
Profile Information
Reporting Name | Available Separately | Always Reported |
---|---|---|
Kappa Free Light Chains | No | Yes |
Lambda Free Light Chains | No | Yes |
Kappa/Lambda Ratio | No | Yes |
Specimen Required
Preferred Container/Tube: Gold SST Top
Acceptable Container/Tube: Gold SST Top
Specimen Volume: 3 mL
Specimen Minimum Volume: 1 mL
Specimen Stability Information
Refrigerated: 21 days
Rejected Due To
- Gross hemolysis
- Gross lipemia
- Microbially contaminated specimens
- Samples containing particulate matter
Reference Values
Kappa Free Light Chains: 3.9-26.0 mg/L
Lambda Free Light Chains: 6.4-22.1 mg/L
Ratio: 0.51-1.72
Method Description
Turbidimetry
Performing Lab
Clinical Lab UH
Day(s) Performed
Monday through Friday (excludes OSU holidays)
Report Available
7 to 9 days
Reporting Name
Immunoglobulin Free Chains
CPT Code Information
83521 x2
LOINC Code Information
36916-5
33944-0
40844-3