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HelpTest Code LABCSFMEP Meningitis/Encephalitis Panel CSF
Clinical Information
Detection of meningitis and encephalitis caused by: Escherichia coli K1 (K1 serotype only), Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis (encapsulated strains only), Streptococcus agalactiae (Group B Strep), Streptococcus pneumoniae, Cytomegalovirus (CMV), Enterovirus, Herpes simplex virus 1 (HSV-1), Herpes simplex virus 2 (HSV-2), Herpes simplex virus 6 (HHV-6), Human parechovirus, Varicella zoster virus (VZV), Cryptococcus neoformans/gattii.
Synonym
- CSFMEP
- BioFire ME Panel
Profile Information
| Reporting Name | Available Separately | Always Reported |
|---|---|---|
| E. coli K1 DNA | No | Yes |
| Haemophilus influenza DNA | No | Yes |
| Listeria monocytogenes DNA | No | Yes |
| Neisseria meningitidis DNA | No | Yes |
| Streptococcus agalactiae DNA | No | Yes |
| Streptococcus pneumoniae DNA | No | Yes |
| CMV DNA | No | Yes |
| Enterovirus RNA | No | Yes |
| HHV-6 DNA | No | Yes |
| HSV-1 DNA | No | Yes |
| HSV-2 DNA | No | Yes |
| Human parechovirus RNA | No | Yes |
| Cryptococcus gatti/neoformans DNA | No | Yes |
| Varicella zoster DNA | No | Yes |
Specimen Required
Preferred Container/Tube: CSF Tube 3
Acceptable Container/Tube: CSF Tube 3, Sterile Container, CSF Tube 1, CSF Tube 2, CSF Tube 4
Specimen Source: CSF
Specimen Volume: 3 mL
Specimen Minimum Volume: 0.5 mL
Reference Values
Not Detected (for all targets)
Interpretation
A negative result does not exclude the possibility of CNS infection and should not be used as the sole basis for diagnosis, treatment, or other management decisions. Negative results may occur when the concentration of organism(s), virus(es), or yeast in the specimen is below the limit of detection. The ME panel does not distinguish between latent and active herpesvirus infections(CMV, HHV-6). This test was performed using a film array methof for the detection of: Escherichia coli K1, Haemophilus influenza, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, Cytomegalovirus, Enterovirus, Herpes Simplex virus 1 and 2, Human Herpesvirus 6, Human parechovirus, Varicella zoster virus, and Cryptococcus neoformans/gatti.
Cautions
This test is only approved for CSV collected via lumbar puncture. It is not at test of cure.
Method Description
Multiplex polymerase chain reaction (PCR)
Performing Lab
Clinical Lab UH
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 day
Reporting Name
Meningitis/Encephalitis Panel
CPT Code Information
87483
LOINC Code Information
82182-7
82183-5
82184-3
82185-0
82186-8
82189-2
82194-2
82192-6
82190-0
82191-8
82193-4
82181-9
82188-4