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Test Code HEM27 DIC Workup

Synonym

  • DIC,DICMIXES
  • Disseminated Intravascular Coagulation Workup
  • Consumptive Coagulopathy Workup

Profile Information

Reporting Name Available Separately Always Reported
PT INR Yes Yes
PTT Yes Yes
Thrombin Time Yes Yes
Fibrinogen Yes Yes
D Dimer Yes Yes

Specimen Required

Preferred Container/Tube: 2 Full Lt. Blue, 3.2% Na Citrate, 1 Lavender EDTA Whole Blood
Acceptable Container/Tube: 1 Full Lt. Blue, 3.2% Na Citrate, 1 Lavender EDTA Whole Blood
Specimen Volume: 3 - 1 mL aliquots Platelet Poor Plasma, 1 - 3ml Lavender Whole Blood
Specimen Minimum Volume: 3-0.5 mL aliquot Platelet Poor Plasma, 1-2mL Lavender Whole Blood

Specimen Collection Information

For Outreach, other than OSU Patient Service Centers: Samples must be processed and received frozen/must remain frozen in transit. 

For sending frozen plasma specimens, process immediately upon receipt. Centrifuge capped specimen tube in accordance with CLSI H21, at a speed and time required to consistently produce platelet-poor plasma (PPP = platelet count <10 K/uL). Transfer PPP into plastic aliquot tubes, cap and freeze. DO NOT transport until specimens are completely frozen.

Specimen Stability Information

Ambient: 
     Whole blood: 1 hours
      Platelet poor plasma: 8 hours
Frozen: 
      Platelet poor plasma: PPP removed from the cells and frozen at -20°C or ideally -70°C.

Rejected Due To

  • Ambient WB specimens >1 hour old
  • Ambient PPP specimens >8 hours old
  • Clotted specimens
  • Underfilled or overfilled tube
  • Hemolysis
  • Icterus
  • Lipemia

Testing Algorithm

If the PTT and/or TT are prolonged, then PTT and/or TT mixing studies will be performed at an additional charge.

Reflex Tests

Reporting Name Available Separately Always Reported
PTT Mixing Studies Yes No
TT Mixing Studies Yes No

Reference Values

PT: 11.9-14.2 sec

INR: 0.9-1.1

PTT: 24.0-34.3 sec

Thrombin Time: 13.0-20.0 sec

Fibrinogen: 220-410 mg/dL

D Dimer: <0.50 mcg/mL FEU

Method Description

PT, PTT, Mixing Studies, Fibrinogen, Thrombin Time: Mechanical Clot Detection

D-Dimer: Optical  measurement at 540 nm

Performing Lab

Clinical Lab UH

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day

 

May be up to 4 days for path interpretation.

Reporting Name

DIC Workup

CPT Code Information

85610
85730
85384
85670
85379
85732 (if appropriate)

LOINC Code Information

5902-2
34714-6
14979-9
46717-5
3255-7
48065-7