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Test Code HEM5 Multimer Analysis, von Willebrand Antigen

Clinical Information

von Willebrand Disease is the most common hereditary bleeding disorder an it may also be acquired. Von Willebrand Factor (VWF) is critical for normal hemostasis; mediating platelet adhesion to the damaged endothelium and protecting Factor VIII from proteolytic degradation in circulation. VWF Multimeric Analysis is used to assist in categorizing disease subtype.

Synonym

  • Multimeric Analysis
  • vWF Multimer
  • Factor Multimeric
  • YMULS

Profile Information

vWF Ag, Multimeric

Specimen Required

1 mL platelet poor plasma, collected in Sodium Citrate (blue top tube). Draw blood in light blue top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within 1 hour of collection. Using pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer, place in plastic vial. Centrifuge a second time and transfer platelet-poor plasma into plastic vial.

Specimen Stability Information

Ambient: unacceptable
Refrigerated: unacceptable
Frozen (preferred): 30 days

Reference Values

See Report

Method Description

Electrophoresis

Performing Lab

Quest Diagnostics Nichols Institute
14225 Newbrook Dr.
Chantilly, VA 20153

Day(s) Performed

Monday - Friday

Report Available

8 days 

Reporting Name

vWF Ag, Multimeric

CPT Code Information

85247

LOINC Code Information

32217-2