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HelpTest Code IMM128 Anti-Phosphatidylcholine Ab
Additional Codes
YAPC
Specimen Required
Specimen Type: Serum
Container/Tube: Red Top or SST
Specimen Volume: 3 mL
Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube is acceptable. Spin down and send 3 mL of serum frozen in a plastic vial.
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
Anti-Phosphatidylcholine PanelSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 30 days | |
| Refrigerated | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| List other reasons for rejection | Microbial contaminants |
Reference Values
Anti-Phosphatidylcholine IgA: <12.0 U/mL
Anti-Phosphatidylcholine IgG: <12.0 U/mL
Anti-Phosphatidylcholine IgM: <12.0 U/mL
Reference Range applies to Antiphosphatidylcholine IgA, IgG & IgM:
Normal <12.0
Equivocal 12.0 – 18.0
Elevated >18.0
Day(s) Performed
Wednesday
Report Available
3 to 11 daysPerforming Laboratory
BioAgilytix DiagnosticsTest Classification
The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one.CPT Code Information
83520/x3
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FCLNE | Anti-Phosphatidylcholine Panel | Not Provided |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z0141 | Anti-Phosphatidylcholine IgA | 13075-7 |
| Z0149 | Anti-phosphatidylcholine IgG | 13073-2 |
| Z0140 | Anti-Phosphatidylcholine IgM | 13074-0 |
Clinical Information
The anti-phospholipid syndrome (APS) is a disorder of recurrent vascular thrombosis associated with persistently positive anticardiolipin (aCL) or lupus anticoagulant tests. In patients with APS, anticardiolipin antibodies bind a variety of charged phospholipids, including phosphatidylethanolimine, as well as they do cardiolipin. Lupus patients also have high titers of autoantibodies to various phospholipids, including
phosphatidylethanolimine.
Presentations of the syndrome include thrombosis of deep veins of the legs, as well as renal, hepatic, inferior vena cava or sagittal veins. Occlusion of the arterial circulation may be manifested as stroke, ischemic retinopathy, myocardial or bowel infarction, or peripheral gangrene. Thrombosis can occur in veins or arteries of any size. Recurrent pregnancy loss also appears to be the result of thrombosis within the placental vasculature.
Anti-phospholipid antibody tests are supplemental tests and should not be used alone for diagnostic purposes. Diagnosis of anti-phospholipid syndrome must be made in conjunction with other clinical indications.