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HelpTest Code LAB21 Carbamazepine Total Level
Clinical Information
Carbamazepine (Tegretol) is used in the control of partial seizures with both temporal lobe and psychomotor symptoms as well as for generalized tonic-clonic seizures. It is also used for analgesia in trigeminal neuralgia. Dosage adjustments are usually guided by monitoring blood levels.
Synonym
- CARB
Specimen Required
Preferred Container/Tube: Mint Green Top
Acceptable Container/Tube: Mint Green Top, Red Top
Specimen Volume: 3 mL
Specimen Minimum Volume: 1 mL
Specimen Stability Information
Ambient: 4 hours
Refrigerated: 5 days
Specimen Collection Information
Outreach Clients: Refrigerate serum as soon as possible after separation from the cells.
Processing instructions: Draw 30 min - 1 hour PRIOR to dose.
Rejected Due To
- Gross hemolysis
- Gross icterus
- Quantity not sufficient
- Quality not acceptable
Reference Values
Therapeutic Range: 4.0-12.0 mcg/mL
Method Description
Competition between drug in the sample and drug labeled with the enzyme glucose-6-phosphate dehydrogenase (G6PDH) for antibody binding sites. Enzyme activity decreases upon binding to the antibody, so the drug concentration in the sample can be measured in terms of enzyme activity. Active enzyme converts oxidized nicotinamide adenine dinucleotide (NAD) to NADH, resulting in an absorbance change.
Performing Lab
Clinical Lab UH
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 day
Reporting Name
Carbamazepine Total
CPT Code Information
80156
LOINC Code Information
3432-2