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HelpTest Code LAB275 Antibody Titer
Clinical Information
Monitoring antibody levels during pregnancy to help assess the risk of hemolytic disease of the newborn.
This test is not useful for monitoring the efficacy of Rh-immune globulin administration.
Synonym
- ABTIT
Profile Information
Includes:
ABO Typing
Rh(D) Typing
Antibody Screen
Direct Antiglobulin Test (Poly)
Antibody Identification
Antibody Titer
Specimen Required
Specimen Type: Whole Blood EDTA
Specimen Volume: 6 mL
Specimen Minimum Volume: 1 mL
Specimen Collection Information
Specimen must arrive within 48 hours of collection. If received >48 hours, Direct Antiglobulin testing will not be performed.
Specimen Stability Information
Ambient: 24 hours
Refrigerated: 7 days
Rejected Due To
- Frozen
- Gross hemolysis
- Sent on heat/ice
- Less than minimum volume
- Missing collector information
- Missing patient identification
Testing Algorithm
If the antibodies detected are too weakly reactive to titer, this test will not be performed and all other testing will be performed and charge.
Reference Values
Negative
Interpretation
The specificity of the maternal alloantibody will be stated. The titer result is the reciprocal of the highest dilution at which macroscopic agglutination (1+) is observed.
Cautions
Recent administration of Rh-immune globulin may cause anti-D to be identified and appear falsely as an alloantibody.
Method Description
Hemagglutination
Performing Lab
Blood Bank University Hospital
Day(s) Performed
Monday through Sunday
Report Available
1 to 5 days
Reporting Name
Antibody Titer - Red Cell
CPT Code Information
86886
Reflex Testing
Direct Antiglobulin Test, IgG
Direct Antiglobulin Test, C3b/d
Antibody Elution testing
Red Cell Antigen Typing
Pathologist Consult