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HelpTest Code LAB303 Factor II Activity
Clinical Information
Detection of specific coagulation factor II deficiency.
Synonym
- FA2
- Factor 2 Activity
- Prothrombin Activity
Specimen Required
Preferred Container/Tube: 3.2% Citrate Blue Top - 2.7 mL
Specimen Volume: 2.7 mL
Acceptable Container/Tube: 3.2% Citrate Blue Top - 1.8 mL
Specimen Volume: 1.8 mL
Platelet poor plasma (PPP):
Specimen Volume: 2 - 1 mL aliquots platelet poor plasma (PPP)
Specimen Minimum Volume: 1 - 1 mL aliquot platelet poor plasma (PPP)
Specimen Collection Information
For Outreach, other than OSU Patient Service Centers: Samples must be processed and received frozen/must remain frozen in transit.
For sending frozen plasma specimens, process immediately upon receipt. Centrifuge capped specimen tube in accordance with CLSI H21, at a speed and time required to consistently produce platelet-poor plasma (PPP = platelet count <10 K/uL). Transfer PPP into plastic aliquot tubes, cap and freeze. DO NOT transport until specimens are completely frozen.
Specimen Stability Information
Ambient:
Whole blood: 4 hours
Platelet poor plasma: 4 hours
Frozen:
Platelet poor plasma: PPP removed from the cells and frozen at -20°C or ideally -70°C.
Rejected Due To
- Ambient specimens >4 hours old
- Clotted specimens
- Underfilled or overfilled tube
- Hemolysis
Reference Values
0-4 days: 26-70 % Activity
5-29 days: 33-93 % Activity
30-89 days: 34-102 % Activity
90-179 days: 45-105 % Activity
180-365 days: 60-116 % Activity
1-5 years: 71-116 % Activity
6-10 years: 67-107 % Activity
11-16 years: 61-104 % Activity
17+ years: 60-150 % Activity
Cautions
Increased in patients taking oral contraceptives. Interpretation of results may be limited if patient is receiving anticoagulant therapy.
Method Description
1 stage clotting assay
Performing Lab
Clinical Lab UH
Day(s) Performed
Monday through Friday (excludes OSU holidays)
Report Available
Same day/1 day
Reporting Name
Factor II Activity
CPT Code Information
85210
LOINC Code Information
32635-5