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HelpTest Code LAB34 Salicylate Level
Clinical Information
This test is not intended for use with low-dose aspirin therapy. Most patients on low daily doses of aspirin for cardiovascular prophylaxis will have serum concentrations near or below the lower limit of the analytical range.
Synonym
- SALI
Specimen Required
Preferred Container/Tube: Mint Green Top
Acceptable Container/Tube: Mint Green Top, Red Top
Specimen Volume: 3 mL
Specimen Minimum Volume: 1 mL
Specimen Stability Information
Ambient: 8 hours
Refrigerated: 5 days
Rejected Due To
- Gross hemolysis
Reference Values
Therapeutic Range: 20.0-30.0 mg/dL
Method Description
Serum is mixed with Reagent 1, which contains antibodies to salicylic acid and the coenzyme nicotinamide adenine dinucleotide (NAD). Subsequently, Reagent 2, which contains salicylic acid labeled with the enzyme glucose‑6‑phosphate dehydrogenase (G6PDH), is added. Salicylic acid in the sample and salicylic acid‑labeled G6PDH compete for antibody binding sites. Enzyme activity decreases upon binding to the antibody, so the salicylic acid concentration in the sample can be measured in terms of enzyme activity. Active enzyme converts oxidized NAD to NADH, resulting in an absorbance change that is measured spectrophotometrically.
Performing Lab
Clinical Lab University East
Clinical Lab James
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 day
Reporting Name
Salicylate Level
CPT Code Information
80179
LOINC Code Information
4024-6