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Test Code LAB448 Tramadol, Urine

Clinical Information

This test is intended to detect tramadol in urine samples. Detection of tramadol in urine indicates recent exposure but cannot be used to determine the dosage or route of administration.

Synonym

  • TramU
  • Ultram
  • ConZip

Specimen Required

Preferred Container/Tube: Urine Container Cup
Acceptable Container/Tube: Urine Container Cup, Urine
Specimen Volume: 5 mL
Specimen Minimum Volume: 1 mL

Specimen Stability Information

Ambient: 14 hours
Refrigerated: 14 days
Frozen: 14 days 

Reference Values

None Detected

 

Cutoff concentrations by liquid chromatography-tandem mass spectrometry:

<25 ng/mL

Interpretation

Numeric results (positive) indicate the measured concentration of drug in the urine sample. Negative results may reflect the absence of drug or drug present below the assay's limit of quantitation. The detection of drugs in urine is dependent on several factors including the amount of drug ingested, time since exposure, individual metabolism, kidney and liver function, urine concentration, and the assay's limit of detection.  Drug concentrations in urine cannot determine the dose, route of administration, or exact time of exposure.

Cautions

Detection of drugs in urine is dependent on urine concentration. False negative results may occur in urine that has been diluted either by direct sample tampering or by ingesting large quantities of water before sample collection. 

Method Description

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Test Classification

This Liquid Chromatography/Mass Spectrometry (LC/MS/MS) test was developed and its performance characteristics determined by the Toxicology Laboratory at The Ohio State University Wexner Medical Center. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high complexity testing. This test is used for clinical purposes and should not be regarded as investigational or for research.

Performing Lab

Clinical Lab UH

Day(s) Performed

Monday through Friday

Report Available

2 to 7 days

Reporting Name

Tramadol, Urine

CPT Code Information

80373
G0480 (if appropriate)