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Test Code LAB73 IgA

Clinical Information

Increased serum immunoglobulin concentrations occur due to polyclonal or oligoclonal immunoglobulin proliferation in hepatic disease (hepatitis, liver cirrhosis), connective tissue diseases, acute and chronic infections, as well as in the cord blood of neonates with intrauterine and perinatal infections. Elevation of IgA may occur in monoclonal gammopathies such as multiple myeloma, primary systemic amyloidosis, monoclonal gammopathy of undetermined significance, and related disorders. Decreased levels are found in patients with primary or secondary immune deficiencies. Electrophoresis is usually required to interpret an elevated immunoglobulin class as polyclonal versus monoclonal. Immunofixation is usually required to characterize a monoclonal protein. 

Synonym

  • IGA

Specimen Required

Preferred Container/Tube: Gold SST Top
Acceptable Container/Tube: Gold SST Top
Specimen Volume: 3 mL
Specimen Minimum Volume: 1 mL

Specimen Stability Information

Ambient: 4 hours
Refrigerated: 5 days

Rejected Due To

  • Gross hemolysis
  • Gross icterus
  • Quantity not sufficient
  • Quality not acceptable

Reference Values

FEMALE MALE
0-30 days: 0-10 mg/dL
31-182 days: ≤42 mg/dL
183-365 days: 6-68 mg/dL
1-3 years: 15-111 mg/dL
4-6 years: 33-166 mg/dL
7-9 years: 28-180 mg/dL
10-12 years: 55-193 mg/dL
13-15 years: 62-241 mg/dL
16-18 years: 69-262 mg/dL
19-59 years: 66-433 mg/dL
60+ years: 90-410 mg/dL
0-30 days: ≤11 mg/dL
31-182 days: ≤40 mg/dL
183-365 days: 1-82 mg/dL
1-3 years: 9-137 mg/dL
4-6 years: 44-187 mg/dL
7-9 years: 58-204 mg/dL
10-12 years: 46-218 mg/dL
13-15 years: 29-251 mg/dL
16-18 years: 68-259 mg/dL
19-59 years: 66-433 mg/dL
60+ years: 90-410 mg/dL

Method Description

Turbidimetry

Performing Lab

Clinical Lab UH

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day

Reporting Name

IgA

CPT Code Information

82784

LOINC Code Information

2458-8