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HelpTest Code LABFIBOB Fibrinogen, Obstetrical
Clinical Information
Identification of disseminated intravascular coagulation, and fibrinolytic activity.
Synonym
- FIB
- Fibrinogen, OB
Specimen Required
Preferred Container/Tube: 3.2% Citrate Blue Top - 2.7 mL
Specimen Volume: 2.7 mL
Acceptable Container/Tube: 3.2% Citrate Blue Top - 1.8 mL
Specimen Volume: 1.8 mL
Platelet poor plasma (PPP):
Specimen Volume: 1 - 1 mL aliquots platelet poor plasma (PPP)
Specimen Minimum Volume: 1 - 0.5 mL aliquot platelet poor plasma (PPP)
Specimen Collection Information
For Outreach, other than OSU Patient Service Centers: Samples must be processed and received frozen/must remain frozen in transit.
For sending frozen plasma specimens, process immediately upon receipt. Centrifuge capped specimen tube in accordance with CLSI H21, at a speed and time required to consistently produce platelet-poor plasma (PPP = platelet count <10 K/uL). Transfer PPP into plastic aliquot tubes, cap and freeze. DO NOT transport until specimens are completely frozen.
Specimen Stability Information
Ambient:
Whole blood: 4 hours
Platelet poor plasma: 8 hours
Frozen:
Platelet poor plasma: PPP removed from the cells and frozen at -20°C or ideally -70°C.
Rejected Due To
- Ambient WB specimens >4 hours old
- Ambient PPP specimens >8 hours old
- Clotted specimens
- Underfilled or overfilled tube
- Hemolysis
- Icterus
- Lipemia
Reference Values
OB 1st Trimester: 244-510 mg/dL
OB 2nd Trimester: 291-538 mg/dL
OB 3rd Trimester: 373-619 mg/dL
Interpretation
Fibrinogen levels may be altered by the normal physiologic changes of pregnancy and should be interpreted considering reference ranges specific to gestational age.
Method Description
Mechanical clot detection of dilute plasma in the presence of excess thrombin.
Performing Lab
Clinical Lab UH
Clinical Lab University East
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 day
Reporting Name
Fibrinogen, Obstetrical
CPT Code Information
85384
LOINC Code Information
3255-7