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HelpTest Code LABXLRP4 LRP4 Autoantibody Test
Clinical Information
Detects anti-LRP4 (low density lipoprotein receptor-related protein 4) in the sera of patients with Myasthenia Gravis (MG). The LRP4 protein activates MuSK kinase activity and promotes the clustering of AChR and their stabilization at the NMJ. Anti-LRP4 antibodies are found in approximately 9.2% (range 2% to 50%) of MG patients who are negative for both anti-AChR and anti-MuSK.
Synonym
- XLRP4
Specimen Required
2 mL serum from Plain Red or Gold SST
Specimen Stability Information
Ambient: 72 hours
Refrigerated (preferred): 25 days
Frozen: 25 days
Reference Values
See Report
Method Description
Immunofluorescent Assay (IFA)
Performing Lab
Athena Diagnostics Inc
200 Forest St, 2nd Floor
Marlborough, MA 01752
Day(s) Performed
As needed
Report Available
14 days
Reporting Name
LRP4 Autoantibody Test
CPT Code Information
86255
LOINC Code Information
19146-0