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Test Code XCIGG4 IgG4 (Immunoglobulin G Subclass 4)

Clinical Information

IgG4-related disease is a systemic inflammatory condition of unknown etiology, most commonly affecting middle-aged and older men. It can involve multiple organ systems, including IgG4-related interstitial pneumonitis and IgG4-related tubulointerstitial nephritis. Elevated serum IgG4 concentrations are observed in at least 50% of patients diagnosed with this disease.Diagnosis may require a tissue biopsy of the affected organ, demonstrating characteristic histological features. Please note: an elevated IgG4 concentration is associated with IgG4-related disease, however, it is not used for a definitive diagnosis.

Synonym

  • IGG4
  • IgG 4
  • IgG Subclass 4

Specimen Required

Preferred Container/Tube: Gold SST Top
Acceptable Container/Tube:  Gold SST Top
Specimen Volume: 1 mL
Specimen Minimum Volume: 0.5 mL

Specimen Stability Information

Refrigerated: 8 days

Rejected Due To

  • Gross hemolysis
  • Gross lipemia
  • Microbially contaminated
  • Containing particulate matter

Reference Values

0-4 months: ≤19.8 mg/dL
5-8 months: ≤20.8 mg/dL
9-14 months: ≤22.0 mg/dL
1 5months -2 years: ≤23.0 mg/dL
2-3 years: ≤49.1 mg/dL
4-6 years: ≤81.9 mg/dL
7-9 years: 1.0-108.7 mg/dL
10-12 years: 1.0-121.9 mg/dL
13-15 years: ≤121.7 mg/dL
16-17 years: ≤111.0 mg/dL
≥18 years: 2.4-121.0 mg/dL

Method Description

Turbidimetry

Performing Lab

Clinical Lab UH

Day(s) Performed

Tuesday and Friday

Report Available

7 to 9 days

Reporting Name

Immunoglobulin G Subclass 4

CPT Code Information

82787

LOINC Code Information

2469-5