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HelpTest Code YAPE Anti-Phosphatidylethanolamine Panel
Additional Codes
YAPE
Specimen Required
Specimen Type: Serum
Container/Tube: Red Top or SST
Specimen Volume: 3 mL
Collection Instructions: Draw blood in a plain ed-top tube(s), serum gel tube is acceptable. After collection, allow blood to clot for 30 minutes. Spin down and send 3 mL of serum frozen in a plastic vial.
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
Anti-Phosphatidylethanolamine PanelSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 30 days | |
| Refrigerated | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| List other reasons for rejection | Specimens other than serum. Microbially contaminated specimens. |
Reference Values
Anti-Phosphatidylethanolamine IgA
<12.0 U/mL
Anti-Phosphatidylethanolamine IgG
<12.0 U/mL
Anti-Phosphatidylethanolamine IgM
<12.0 u/mL
Reference Range applies to Anti-Phosphatidylethanolamine IgA, IgG, & IgM
Normal: <12.0
Equivocal: 12.0-18.0
Elevated: >18.0
Day(s) Performed
Wednesday
Report Available
3 to 11 daysPerforming Laboratory
BioAgilytix DiagnosticsTest Classification
The performance characteristics of the listed assays were validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared these tests. The results of these assays can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays.CPT Code Information
83520 x 3
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FPHET | Anti-Phosphatidylethanolamine Panel | Not Provided |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z0143 | Anti-Phosphatidylethanolamine IgA | 13078-1 |
| Z0150 | Anti-Phosphatidylethanolamine IgG | 13076-5 |
| Z0142 | Anti-Phosphatidylethanolamine IgM | 13077-3 |
Clinical Information
The anti-phospholipid syndrome (APS) is a disorder of recurrent vascular thrombosis associated with persistently positive anticardiolipin (aCL) or lupus anticoagulant tests. In patients with APS, anticardiolipin antibodies bind a variety of charged phospholipids, including phosphatidylethanolamine, as well as they do cardiolipin. Lupus patients also have high titers of autoantibodies to various phospholipids, including phosphatidylethanolamine.
Presentations of the syndrome include thrombosis of deep veins of the legs, as well as renal, hepatic, inferior vena cava or sagittal veins. Occlusion of the arterial circulation may be manifested as a stroke, ishemic retinopathy, myocardial or bowel infarction, or peripheral gangrene. Thrombosis can occur in veins or arteries of any size. Recurrent pregnancy loss also appears to be the result of thrombosis within the placental vasculature.
Anti-phosphatidyl antibody tests are supplemental tests and should not be used alone for diagnostic purposes. Diagnosis of anti-phospholipid syndrome must be made in conjunction with other clinical indications.