Clinical Information

This test is used for the diagnosis of vitamin D deficiency or hypervitaminosis D, differential diagnosis of causes of rickets and osteomalacia, and monitoring vitamin D replacement therapy. Long term use of anticonvulsant medications may result in vitamin D deficiency that could lead to bone disease; the anticonvulsants most implicated are phenytoin, phenobarbital, carbamazepine, and valproic acid. Newer antiseizure medications have not been studied or are not thought to contribute to vitamin D deficiency.